Medicinal Chemistry

Rudi van Eldik , Peter J. Sadler 지음

elsevier 2020년 02월 20일 출간

작품소개

책소개

Medicinal Chemistry, Volume 75, the latest release in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers that empowers readers to pursue new developments in each field. Users will find this to be a comprehensive overview of recent findings and trends from the last decade that covers various kinds of inorganic topics, from theoretical oriented supramolecular chemistry, to the quest for accurate calculations of spin states in transition metals.Provides the authority and expertise of leading contributors from an international board of authorsPresents the latest release in the Advances in Inorganic Chemistry seriesIncludes the latest information on medicinal chemistry

목차

1. 150 Years of the periodic table: New medicines and diagnostic agents Cinzia Imberti and Peter J. Sadler 2. Medicinal inorganic chemistry: New perspectives and targets for the periodic table Nicholas P. Farrell 3. Anti-cancer gold, platinum and iridium compounds with porphyrin and/or N-heterocyclic carbene ligand(s) Ka-Chung Tong, Di Hu, Pui-Ki Wan, Chun-Nam Lok and Chi-Ming Che 4. Metal N-heterocyclic carbene complexes in medicinal chemistry Ingo Ott 5. Rational design of anticancer platinum(IV) prodrugs Shuren Zhang, Xiaoyong Wang and Zijian Guo 6. Bismuth drugs as antimicrobial agents Runming Wang, Hongyan Li, Tiffany Ka-Yan Ip and Hongzhe Sun 7. Antimony and bismuth as antimicrobial agents Rebekah N. Duffin, Melissa V. Werrett and Philip C. Andrews 8. Pharmacophore conjugation strategy for multi-targeting metal-based anticancer complexes Yao Zhao, Yan Kang, Fengmin Xu, Wei Zheng, Qun Luo, Yanyan Zhang, Feifei Jia and Fuyi Wang 9. Organelle-targeting metal anticancer agents Lina Xie, Ruilin Guan, Thomas W. Rees and Hui Chao 10. From the hypothesis-driven development of organometallic anticancer drugs to new methods in mode of action studies Muhammad Hanif and Christian G. Hartinger 11. Design and applications of catalytic metallodrugs containing the ATCUN motif Zhen Yu and James A. Cowan 12. The eyes have it: Using X-ray crystallography to determine the binding modes of medically relevant ruthenium/DNA complexes Kane Thomas McQuaid and Christine Janet Cardin 13. Interaction of metal complexes with G-quadruplex DNA Ramon Vilar 14. CXCR4-targeted metal complexes for molecular imaging Isaline Renard and Stephen J. Archibald

작가정보

저자(글) Rudi van Eldik

저자(글) Peter J. Sadler