Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet

Colin R. Martin , Victor R. Preedy , Rajkumar Rajendram 지음

elsevier 2021년 06월 25일 출간

작품소개

책소개

Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with proper and abnormal development. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurodevelopment. In addition, the book examines in vitro and in vivo modeling of development with stem cells and model systems.Provides the most comprehensive coverage of a broad range of topics relating to the neuroscience of developmentFeatures sections on the genetics of developmental conditions and accompanying behaviorContains an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding in each chapterFocuses on neurodevelopmental disorders and environmental factors that influence neural developmentIncludes more than 500 illustrations and tables

목차

I. Genetics, Molecular and Celluar Biology 1. Hereditary motor neuropathies 2. Dopamine transporter (DAT1) polymorphism and development 3. Genome wide association studies (GWAS) and neurodevelopment: Autism spectrum disorder 4. SNPs and cerebral palsy 5. Epigenetic regulation of cortical neurogenesis 6. Functions and dynamics of axonal mitochondria 7. Linking apoptosis and caspases in fetal neural tube defects 8. Brain oxidative stress in Down syndrome 9. Linking Adhesion GPCRs to Glial Cell Development and Function 10. Immunoglobulin cell adhesion molecule superfamily and neurodevelopment 11. Brain-derived neurotrophic factor (BDNF) and neurogenesis 12. slc7a5 and neural development 13. Linking SOX3, SRY and disorders of neurodevelopment 14. Neuronal Src-homology-2 (SH2)B adaptor protein-1 (Sh2b1) and brain growth 15. Effects of extrinsic factors and intracellular signalling and transcription factors regulating the development and cell fate of spinal cord ependymal cells 16. Signaling molecules controlling oligodendrocyte development and brain myelination II. Neurological and Imaging Features 17. Fetal brain structures: imaging oriented 18. Four-dimensional (4D) ultrasonography: Methods, uses and fetal neuroscience 19. Linking histology and neurological development of the fetal and infant brain 20. Development of Corticospinal tract axons: from embryonic stage to adulthood 21. Vascular endothelial growth factor (VEGF) and neurodevelopment 22. Brain-wide connectivity architecture: developmental aspects 23. Development and pathology of the germinal matrix 24. Development of the GABAergic network in the mouse spinal cord 25. Postnatal development, electrophysiology and sensory sural nerves 26. Neuroscience of the developing axonal strata in the human fetal brain 27. Neuroactive steroids and neurodevelopment 28. Voltage and ligand-gated ion channels appearance and function in neurodevelopment 29. Features of brain development over 13 years in pr

작가정보

저자(글) Colin R. Martin

저자(글) Victor R. Preedy

저자(글) Rajkumar Rajendram