Exosomes: A Clinical Compendium

Lawrence R. Edelstein , John R. Smythies , Peter J. Quesenberry , Denis Noble 지음

elsevier 2019년 10월 16일 출간

작품소개

책소개

Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function.Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck.Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative effortsTwenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

목차

1. Exosome Basic Mechanisms 2. Methods for exosome isolation and characterization 3. Exosomes, microvesicles, and their friends in solid tumors 4. Hematologic malignancies: the exosome contribution in tumor progression 5. Physiological and pathological functions of prostasomes: From basic research to clinical application 6. The function and therapeutic use of exosomes in bacterial infections 7. Emerging therapeutic roles of exosomes in HIV-1 infection 8. Extracellular vesicles in parasitic disease 9. Exosomes as intercellular communication messengers for cardiovascular and cerebrovascular diseases 10. Exosomes in Cutaneous Biology and Dermatologic Disease 11. Exosomes in Nephrology 12. Extracellular vesicles in neurodegenerative disorders 13. Extracellular vesicles in fibrotic diseases: New applications for fibrosis diagnosis and treatment 14. Mechanisms of exosome-mediated immune cell crosstalk in inflammation and disease 15. Exosomes in Metabolic Syndrome 16. Potential Role of Exosomes In Reproductive Medicine And Pregnancy 17. Exosomes in Respiratory Disease 18. Exosomes in Retinal Diseases 19. MSC-exosomes in regenerative medicine 20. The potential of exosomes as theragnostics in various clinical situations 21. Exosomes, Gemmules, Pangenesis and Darwin

작가정보

저자(글) Lawrence R. Edelstein

저자(글) John R. Smythies

저자(글) Peter J. Quesenberry

저자(글) Denis Noble