Platelets

Alan D. Michelson , Marco Cattaneo , Andrew Frelinger , Peter Newman 지음

elsevier 2019년 03월 07일 출간

작품소개

책소개

Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.Comprehensive and definitive source of state-of-the-art knowledge about platelets Integrates the entire field of platelet biology, pathophysiology, and clinical medicineWritten for clinicians, pathologists and scientists by 142 world-renowned experts from 18 countriesCompletely revised and updated, with 11 new chapters on topics such as platelet glycobiology, the platelet transcriptome, platelet inhibitory receptors, platelet function testing in clinical research trials, therapeutic platelet-rich plasma in wound healing, and new antiplatelet drugsFull color textbook with over 250 illustrations and 15,000 references

목차

PART I: Platelet Biology 1. The Evolution of Mammalian Platelets 2. Megakaryocyte Development and Platelet Formation 3. The Structure of Resting and Activated Platelets 4. Platelet Glycobiology and the Control of Platelet Function and Lifespan 5. Platelet Genomics 6. Platelet MicroRNAs 7. The Platelet Transcriptome in Health and Disease 8. The Platelet Proteome 9. Platelet Receptors 10. The Glycoprotein Ib-IX-V Complex 11. GPVI and CLEC-2 12. Integrin 慣IIb棺3 13. Protease-Activated Receptors 14. The Platelet P2 Receptors 15. Platelet Inhibitory Receptors 16. Interactions Between Platelets, Leukocytes, and the Endothelium 17. Inhibition of Platelet Function by the Endothelium 18. Platelet Signal Transduction 19. Platelet Secretion 20. Hemostatic Thrombus Formation in Flowing Blood 21. Interactions Between Platelets and the Coagulation System 22. Platelet-Derived Extracellular Vesicles 23. Regulation of Fibrinolysis by Platelets 24. The Role of Platelets in Angiogenesis 25. Platelet Function in the Newborn PART II: The Role of Platelets in Disease 26. The Role of Platelets in Atherothrombosis 27. The Role of Platelets in Diabetes Mellitus 28. The Role of Platelets in Inflammation 29. The Role of Platelets in Antimicrobial Host Defense 30. The Role of Platelets in Tumor Growth, Metastasis, and Immune Evasion 31. The Role of Platelets in Sickle Cell Disease PART III: Clinical Tests of Platelet Function 32. Platelet Counting 33. Clinical Tests of Platelet Function 34. Platelet Aggregation 35. Flow Cytometry 36. Laboratory Monitoring of Antiplatelet Therapy 37. Platelet Function Testing in Clinical Research Trials PART IV: Disorders of Platelet Number and/or Function 38. The Clinical Approach to Disorders of Platelet Number and Function 39. Immune Thrombocytopenia (ITP) 40. Drug-Induced Thrombocytopenia 41. Heparin-Induced Thrombocytopenia 42. Thrombotic Thrombocytopenic Purpura and Hemolytic-Uremic Syndromes 43. Thromb

출판사 서평

Accolades for Previous Editions:Best Book in Medical Science Award --Association of American PublishersHighly Commended Prize (Internal Medicine) --British Medical Association Medical Book Awards"Belongs on the bookshelf of every clinician who assesses patients with platelet disorders" --The Lancet"Landmark" --New England Journal of Medicine"This is a fantastic resource for anyone who treats patients with platelet disorders or is engaged in platelet or megakaryocyte-based research" --British Journal of Haematology

작가정보

저자(글) Alan D. Michelson

저자(글) Marco Cattaneo

저자(글) Andrew Frelinger

저자(글) Peter Newman