Neuropathology of Drug Addictions and Substance Misuse Volume 3

Victor R. Preedy 지음

elsevier 2016년 04월 25일 출간

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Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader??s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictionsFills an existing gap in the literature by serving as a ??one-stop-shopping? synopsis of everything to do with the neuropathology of drugs of addiction and substance misuseIncludes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, full referencesOffers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body

Part I. Principles of Addictions, Overviews, Detailed Processes and Mechanisms Section A. General Aspects Chapter 1. Drugs and the Human Envirome Chapter 2. Psychoactive Plants Used during Religious Rituals Chapter 3. Substance Use Disorders and Comorbid Mental Illness: A Focus on Epidemiological Data Regarding Mood and Anxiety Disorders Chapter 4. Mephedrone and Mephedrone-Based Cocktails: Market, Analysis, Mechanisms of Action, and Toxicity Chapter 5. Substance-Induced Psychosis: Conceptual and Diagnostic Challenges in Clinical Practice Chapter 6. Sleep and Drug Addiction Section B. Molecular and Cellular Aspects Chapter 7. Hypothalamic and Midbrain Cells, Tyrosine Hydroxylase, and Implications for Drug Addiction Chapter 8. Oxytocin: Providing New Avenues for Treating and Understanding Problematic Drug Use Chapter 9. Role of D2-like Heteroreceptor Complexes in the Effects of Cocaine, Morphine, and Hallucinogens Chapter 10. Glutamate Receptors and Drug Addiction Chapter 11. Effect of Interacting Nonsteroidal Anti-Inflammatory Agents (NSAIDs) and Opioids on Mood: Pharmacodynamic Considerations in Misuse and Abuse Chapter 12. A Mini-Review on Different Commonly Used Abusive Drugs and the Interactions of These Drugs and Chinese Herbs Chapter 13. Interaction of Drugs of Addiction with DNA Chapter 14. Drugs of Abuse and DNA Methylation in the Brain: Ethanol, Cocaine, Amphetamine??Methamphetamine, Heroin, Antidepressants, and Antipsychotics Chapter 15. Orexin/Hypocretin System and Drug Addiction Chapter 16. Reverse Translational Implications of Genome-Wide Association Studies for Addiction Genetics Chapter 17. Polymorphisms in the Delta Opioid Receptor Gene (OPRD1) and Drug Addiction: Candidate Genes, Transgenic Mouse Models

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저자(글) Victor R. Preedy

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