Accurate Results in the Clinical Laboratory

Amitava Dasgupta 지음

elsevier 2013년 01월 22일 출간

작품소개

책소개

This practical, easy-to-use guide addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.Practical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy referenceFocus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooksCovers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing

목차

Chapter 1. Variation, Errors, and Quality in the Clinical Laboratory Chapter 2. Effect of Age, Gender, Diet, Exercise and Ethnicity on Laboratory Test Results Chapter 3. Effect of patient preparation, specimen collection, anticoagulants and preservatives on laboratory tests Chapter 4. Sample processing and specimen misidentification issues Chapter 5. Hemolysis, lipemia and high bilirubin: effect on laboratory tests Chapter 6. Immunoassay design and mechanism of interferences Chapter 7. Effect of herbal remedies on clinical laboratory tests Chapter 8. Challenges in routine clinical chemistry: analysis of small molecules Chapter 9. Challenges in routine clinical chemistry: proteins and enzymes Chapter 10. Sources of inaccuracy in biochemical genetics analysis Chapter 11. Challenges in endocrinology testing Chapter 12. Pitfalls in tumor marker testing Chapter 13. Issues of interferences in therapeutic drug monitoring Chapter 14. Limitations of drugs of abuse testing Chapter 15. Challenges in confirmation testing for drugs of abuse Chapter 16. Alcohol determination using automated analyzers: limitations and pitfalls Chapter 17. Pre-analytical issues and interferences in transfusion medicine tests Chapter 18. Critical issues in immunology and serology testing Chapter 19. Sources of errors in hematology and coagulation testing Chapter 20. Challenges in Clinical Microbiology Testing Chapter 21. Sources of errors in molecular testing Chapter 22. Problems in Pharmacogenomics Testing

출판사 서평

"Dasgupta and Sepulveda offer clinicians and laboratory scientists a guide to error detection and correction in the clinical laboratory that addresses sources of errors in analytical methods and sources of pre-analytical variation."--Reference and Research Book News, August 2013 "This is a very helpful book correlating nonanalytical measurement errors or disease states with anticipated effects on laboratory test results. This would be a must for the laboratory medicine resident who has to explain why results don't correlate with clinical disease."--Doody.com, August 9, 2013

작가정보

저자(글) Amitava Dasgupta