Intercellular Signaling in Development and Disease

Ralph A. Bradshaw , Edward A. Dennis 지음

elsevier 2011년 04월 05일 출간

작품소개

책소개

Required reading for anyone involved in cell signaling research with articles written and edited by experts in the field. This title covers disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, andinflammatory bowel disease, along with up-to-date research on signaling systems and mutations intranscription factors that provide new targets for treating disease.Articles written and edited by experts in the fieldThematic volume covering disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel diseaseUp-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

목차

The fourth volume includes chapters 294 to 340 Signaling From Intracellular Compartments 294 . Protein Quality Control in the Endoplasmic Reticulum 295 . Quality Control and Quality Assurance in the Mitochondrion 296 . Protein Quality Control in Peroxisomes: Ubiquitination of the Peroxisomal Targeting Signal Receptors 297 . Mitochondrial Dynamics: Fusion and Division 298 . The SREBP Pathway: Gene Regulation through Sterol Sensing and Gated Protein Trafficking 299 . Regulating Endoplasmic Reticulum Function through the Unfolded Protein Response 300 . Signaling Pathways from Mitochondria to the Cytoplasm and Nucleus 301 . Apoptosis Signaling: A Means to an End 302 . Regulation of Cell Cycle Progression 303 . Signaling During Organelle Division and Inheritance: Peroxisomes 304 . Signaling at the Nuclear Envelope 305 . Bidirectional Crosstalk between Actin Dynamics and Endocytosis 306 . Signaling in Autophagy Related Pathways Cell -Cell and Cell-Matrix Interaction 307 . Overview of Cell - Cell and Cell - Matrix Interactions 308 . Interactive Signaling Pathways in the Vasculature 309 . Signaling Pathways Involved in Cardiogenesis 310 . Regulatory Signaling in Pancreatic Organogenesis: Implications for Aberrant Signaling in Pancreatic Cancer 311 . Trophic Effects of Gut Hormones in the Gastrointestinal Tract 312 . The Neurotrophin Factors 313 . Cell to Cell and Cell-Matrix Interactions in Bone 314 . Cell-Cell Signaling in the Testis and Ovary 315 . Signal Transduction in T Lymphocytes 316 . Signal Transduction via the B Cell Antigen Receptor: A Crucial Regulator of B Cell Biology 317 . Signaling Pathways in the Normal and Neoplastic Breast 318 . Kidney 319 . Cytokines and Cytokine Receptors Regulating Cell Survival, Proliferation, and Differentiation

출판사 서평

"The Cell Signaling Collection consists of four independent volumes which reprint articles from the second edition of the carefully selected to alert medical and biological scientists to recent developments in the study of cellular signaling. This volume contains 57 articles exploring transduction mechanisms. After an overview of intracellular signaling, they cover phosporylation and dephosphorylation in kinases and phosphates, lipid signaling, cyclic nucleotides, and G proteins. The other volumes cover the functioning of transmembrane receptors, the regulation of organelle and cell compartment signaling, and intracellular signaling in development and disease."--Reference and Research Book News "For professionals, graduate researchers, and graduate students in biochemistry, biology, genetics, and biomedicine, Dennis (chemistry and biochemistry and pharmacology, U. of California, San Diego) and Bradshaw (chemistry and pharmaceutical chemistry, U. of California, San Francisco) bring together 52 articles from the authors' on cell-cell signaling, signaling development, and signaling in disease. A group of biologists, chemists, oncologists, surgeons, and other scientists from the US, Europe, Singapore, and Australia emphasize the role of cell-cell interaction and organ and tissue effects in signaling activities and their disease implications. They do not cover other aspects of cell signaling like transmembrane receptor structure, receptor organization and function, intracellular signaling mechanisms, and transcriptional activation and responses in other organelles."--Reference and Research Book News

작가정보

저자(글) Ralph A. Bradshaw

저자(글) Edward A. Dennis