The Human Genome

R. Scott Hawley , Catherine A. Mori 지음

elsevier 1998년 10월 01일 출간

작품소개

책소개

The Human Genome: A User's Guide provides a concise discussion of contemporary and relevant topics in human genetics. It begins coverage of the fundamental concepts of genetics and heredity, then illustrates these concepts as they relate to the development of human sexual differentiation and sexuality. The book describes the role of the X and Y chromosomes, the role of hormone-controlled differential gene expression in sex determination, and the role of genetics in sexual orientation and sex-role development. The Human Genome discusses the interface between science and society, covering the basic intellectual processes that underlie genetic analysis and gene therapy. It also looks at the use of cloning techniques to search for genes responsible for such human disease states as cystic fibrosis, cancer, AIDS, and mental illness. Written in an inviting and engaging style, The Human Genome meets the interests and answers the questions of today's students.Key Features:* Offers a concise discussion of contemporary human genetics and relevant topics* Accessible to the reader with no formal science background* Reviews the fundamental principles that underlie genetic analysis, prenatal diagnosis, and gene therapy* Makes use of the most up-to-date information on the genetic aspects of AIDS, sexual orientation, and gender research* Includes a controversial discussion of gene therapy and the quot;oldquot; and quot;newquot; eugenics * Presents stories of real and fictional people, bringing the concepts of human inheritance quot;to lifequot;* Appropriate as supplemental or recommended reading for courses on human genetics and reproductive biology for majors as well as on genetics for non-majors or sexuality and human development for psychology students

목차

The Basics of Heredity:The Answer in a Nut Shell: Genes, Proteins, and the Meaning of Life.Mendel and the Concept of the Gene.How Genes Work: The Story of How Genes Encode Proteins or "The Central Dogma of Molecular Biology."How Genes Move: Chromosomes and the Physical Basis of the Laws of Mendel.Absent Essentials and Monkey Wrenches: How Mutations Produce a Phenotype.How Genes Determine Our Sex.Sex and Chromosomes, Sex and Hormones, Sex and.... Sex Causes Problems: The Inactivation of the Second X Chromosome.Gender Identity and Sexual Orientation.When Meiosis or Mendelian Inheritance Fails.Failed Chromosome Segregation and the Etiology of Down's Syndrome.Extreme Mutation: Triplet Repeat Syndromes. Imprinting or Epigenetic Changes in Genes and Chromosomes.Human Genes.Introduction to Gene Cloning.DNA Polymorphisms as Genetic Markers in Humans (and the Miracle of PCR).Human Gene Mapping: A General Approach.Cystic Fibrosis,Mammoth Genes: Muscular Dystrophy and Neurofibromatosis.Genes and Cancer.Interactions of Genes and the Environment. Multifactorial Inheritance: Towards Finding the Genes for Manic Depression and Schizophrenia.The Monoamine Oxidose A Gene and a Genetic Basis for Criminality?Genetics of the Human AIDS Virus.Prenatal Diagnosis.Methods of Prenatal Diagnosis.Potential for Gene Therapy.Epilogue: Fears, Faith and Fantasies.

출판사 서평

"The examples are excellent and the topics covered are just the ones you'd like to see...There is a real need for a text on this topic that goes beyond the very introductory concepts, but is not so advanced as to be unusable outside an advanced genetics course. This book clearly fits that need."-ROBERT HOLMGREN, Northwestern University"This textbook relates the WOW! aspects of human genetics...It will be a valuable resource for teachers and students who want to, and need to, understand human genetics at a basic level so as to unravel new findings reported in the lay press on a daily basis."-STEPHANIE SHERMAN, Emory University School of Medicine"...a wonderful addition to the human genetics landscape."-TERRY HASSOLD, Case Western Reserve University

작가정보

저자(글) R. Scott Hawley

저자(글) Catherine A. Mori